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KMID : 0896219910120010771
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Journal of Daegu Health College
1991 Volume.12 No. 1 p.771 ~ p.783
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Identification of Gene Locus in Animals
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Lim Sang-Kyu
Kim Tae-Sun
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Abstract
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Mapping of gene locus in animals is the basic step to manipulate genes for the purpose of developing superior performances and protecting disease. However, we do not know how many genes are contributed to the tram and where it is located on the chromosomes. Research for the identification of gene locations in animals is infant stage, but successful resuite in gene mapping of the human and experimental animal had been applied to disease, etiology of cancer and gene manipulation. There are two different approachs toward the mapping of genes : · Gene transfer of hybrid clones between animal somatic cells and transformed mutant cells(somatic cell hybridization and chromosome mediated gene transfer). · Direct assignment of genes by in situ hybridization of DNA of a specific type to fixed animal chromosomes. This study was described the methods and strategies in mapping genes in animals.
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KEYWORD
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